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Article

Genetic Spectrum and Characteristics of Hereditary Optic Neuropathy in Taiwan.

Genes - 31 Aug 2021

Lin Chao-Wen, Huang Ching-Wen, Luo Allen Chilun, Chou Yuh-Tsyr, Huang Yu-Shu, Chen Pei-Lung, Chen Ta-Ching

Abstract excerpt

Hereditary optic neuropathy (HON) is a group of genetically heterogeneous diseases that cause optic nerve atrophy and lead to substantial visual impairment. HON may present with optic nerve atrophy only or in association with various systemic abnormalities. Although a genetic survey is indispensa...

Topics

Adolescent
Adult
Aged
Child
Child, Preschool
DNA Mutational Analysis
Female
GTP Phosphohydrolases
Genetic Counseling
Genetic Testing
Humans
Male
Membrane Proteins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Middle Aged

Mutation

Optic Atrophy, Autosomal Dominant

Optic Atrophy, Hereditary, Leber

Taiwan

Source

Open in PubMed Open full text

Identifiers

PMID: 34573359
DOI: 10.3390/genes12091378
PMCID: PMC8467776

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-34573359-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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