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Article

Genomic Aberrations Associated with the Pathophysiological Mechanisms of Neurodevelopmental Disorders.

Cells - 4 Sept 2021

Yamamoto Toshiyuki

Abstract excerpt

Genomic studies are increasingly revealing that neurodevelopmental disorders are caused by underlying genomic alterations. Chromosomal microarray testing has been used to reliably detect minute changes in genomic copy numbers. The genes located in the aberrated regions identified in patients with neurodevelopmental disorders may be associated with the phenotypic features. In such cases, haploinsufficiency is...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 34571966
DOI: 10.3390/cells10092317
PMCID: PMC8470284

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