Long-term impact of congenital toxoplasmosis on phenotypic and functional features of circulating leukocytes from infants one year after treatment onset.

doi:10.1016/j.clim.2021.108859

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Article

Long-term impact of congenital toxoplasmosis on phenotypic and functional features of circulating leukocytes from infants one year after treatment onset.

Clinical immunology (Orlando, Fla.) - 1 Nov 2021

de Araújo Thádia Evelyn, Gomes Angelica Oliveira, Coelho-Dos-Reis Jordana Grazziela, Carneiro Ana Carolina Aguiar Vasconcelos, Machado Anderson Silva, Andrade Gláucia Manzan Queiroz, Vasconcelos-Santos Daniel Vitor, Januário José Nélio, Peruhype-Magalhães Vanessa, Teixeira-Carvalho Andréa, Vitor Ricardo Wagner Almeida, Antonelli Lis Ribeiro do Valle, Ferro Eloisa Amalia Vieira, Martins-Filho Olindo Assis

Abstract excerpt

Changes in immune response of children with congenital toxoplasmosis (CT) regarding infection evolution and therapeutic intervention was addressed. Infants with CT presented increased counts of monocytes, CD3-CD16-CD56High, CD3+CD56+ and CD4+ T-cells 1-year after treatment onset (TOXO1-yearAT). Smaller numbers of CD3-CD16-CD56+ and TCRγδ+ T-cells were specifically observed in infants with retinochoroidal lesions...

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PMID: 34563685
DOI: 10.1016/j.clim.2021.108859

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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