Article
A random forest model based on core genome allelic profiles of MRSA for penicillin plus potassium clavulanate susceptibility prediction.
Microbial genomics - 1 Sept 2021
Zhuang Hemu, Zhu Feiteng, Lan Peng, Ji Shujuan, Sun Lu, Chen Yiyi, Wang Zhengan, Jiang Shengnan, Zhang Linyue, Zhu Yiwei, Jiang Yan, Chen Yan, Yu Yunsong
Abstract excerpt
Treatment failure of methicillin-resistant Staphylococcus aureus (MRSA) infections remains problematic in clinical practice because therapeutic options are limited. Penicillin plus potassium clavulanate combination (PENC) was shown to have potential for treating some MRSA infections. We investigated the susceptibility of MRSA isolates and constructed a drug susceptibility prediction model for the phenotype of the...
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