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Article

Familial Hypercholesterolemia in Patients with Acute Coronary Syndrome: Genetic Insights from EXPLORE-J.

Journal of atherosclerosis and thrombosis - 1 Aug 2022

Harada-Shiba Mariko, Ako Junya, Hirayama Atsushi, Nakamura Masato, Nohara Atsushi, Sato Kayoko, Murakami Yoshitaka, Koshida Ryusuke, Ozaki Asuka, Arai Hidenori

Abstract excerpt

AIM: Genetic testing can provide a definitive diagnosis of familial hypercholesterolemia (FH). However, accessibility of genetic testing may be limited in certain countries where it is not considered "standard of care," including Japan. In addition, mutations responsible for FH cannot be identified in approximately 30% of patients. METHODS: EXPLORE-J is a multicenter, prospective, observational study of patients...

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Share to Acute Coronary Syndrome
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Hyperlipoproteinemia Type II

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Share to Proprotein Convertase 9

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Source

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Identifiers

PMID: 34526433
DOI: 10.5551/jat.62989
PMCID: PMC9371751

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