Article
Oral Phenotype and Salivary Microbiome of Individuals With Papillon-Lefèvre Syndrome.
Frontiers in cellular and infection microbiology - 1 Jan 2021
Lettieri Giulia Melo, Santiago Luander Medrado, Lettieri Giancarlo Crosara, Borges Luiz Gustavo Dos Anjos, Marconatto Letícia, de Oliveira Laudimar Alves, Damé-Teixeira Nailê, Salles Loise Pedrosa
Abstract excerpt
Papillon-Lefèvre syndrome (PLS) is an autosomal recessive rare disease, main characteristics of which include palmoplantar hyperkeratosis and premature edentulism due to advanced periodontitis (formerly aggressive periodontitis). This study aimed to characterize the oral phenotype, including salivary parameters, and the salivary microbiome of three PLS sisters, comparatively. Two sisters were toothless (PLSTL1...
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