Article
[Thalassemia in Japan].
[Rinsho ketsueki] The Japanese journal of clinical hematology - 1 Jan 2021
Wada Hideho
Abstract excerpt
Thalassemia is caused by a reduced production of one globin chain due to a quantitative imbalance between the α-globin and non-α-globin chains that make up the hemoglobin. It is classified into α- and β-thalassemia and characterized by microcytosis with polycythemia, and a Mentzer index of ≤13 aids in the diagnosis. In the genetic analysis of α-thalassemia, the Southeast Asian type was found to be the most common...
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