Article
Development of the pupillary light reflex from 9 to 24 months: association with common autism spectrum disorder (ASD) genetic liability and 3-year ASD diagnosis.
Journal of child psychology and psychiatry, and allied disciplines - 1 Nov 2021
Fish Laurel A, Nyström Pär, Gliga Teodora, Gui Anna, Begum Ali Jannath, Mason Luke, Garg Shruti, Green Jonathan, Johnson Mark H, Charman Tony, Harrison Rebecca, Meaburn Emma, Falck-Ytter Terje, Jones Emily J H
Abstract excerpt
BACKGROUND: Although autism spectrum disorder (ASD) is heritable, the mechanisms through which genes contribute to symptom emergence remain unclear. Investigating candidate intermediate phenotypes such as the pupillary light reflex (PLR) prospectively from early in development could bridge genotype and behavioural phenotype. METHODS: Using eye tracking, we longitudinally measured the PLR at 9, 14 and 24 months in...
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