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Information needs on breast cancer genetic and non-genetic risk factors in relatives of women with a BRCA1/2 or PALB2 pathogenic variant.

Breast (Edinburgh, Scotland) - 1 Dec 2021

Brédart Anne, De Pauw Antoine, Anota Amélie, Tüchler Anja, Dick Julia, Müller Anita, Kop Jean-Luc, Rhiem Kerstin, Schmutzler Rita, Devilee Peter, Stoppa-Lyonnet Dominique, Dolbeault Sylvie

Abstract excerpt

OBJECTIVES: Comprehensive breast cancer (BC) risk models integrating effects of genetic (GRF) and non-genetic risk factors (NGRF) may refine BC prevention recommendations. We explored the perceived information received on BC risk factors, and related characteristics, in female relatives of women with a BRCA1/2 or PALB2 pathogenic variant, undergoing BC risk assessment using the CanRisk© prediction tool. METHODS:...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 34455229
DOI: 10.1016/j.breast.2021.08.011
PMCID: PMC8403756

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