Article
Comparative Characterization and Pathogenicity of a Novel Porcine Epidemic Diarrhea Virus (PEDV) with a Naturally Occurring Truncated ORF3 Gene Coinfected with PEDVs Possessing an Intact ORF3 Gene in Piglets.
Viruses - 7 Aug 2021
Lu Ying, Huang Weijian, Zhong Lian, Qin Yibin, Liu Xueting, Yang Chunjie, Wang Ruomu, Su Xueli, Du Chen, Mi Xue, Wang Hejie, He Ying, Zhao Wu, Chen Ying, Wei Zuzhang, Ouyang Kang
Abstract excerpt
Coinfection caused by various genotypes of porcine epidemic diarrhea virus (PEDV) is a new disease situation. We previously reported the coexistence of PEDV strains containing different ORF3 genotypes in China. In this study, the PEDV strains 17GXCZ-1ORF3d and 17GXCZ-1ORF3c were isolated and plaque-purified from the same piglet, which had a natural large deletion at the 172-554 bp position of the ORF3 gene or...
Topics
- Animals
- Chlorocebus aethiops
- Coinfection
- Coronavirus Infections
- Diarrhea
- Genotype
- Open Reading Frames
- Phylogeny
- Porcine epidemic diarrhea virus