Article
Characterization of a Lineage C.36 SARS-CoV-2 Isolate with Reduced Susceptibility to Neutralization Circulating in Lombardy, Italy.
Viruses - 31 Jul 2021
Castelli Matteo, Baj Andreina, Criscuolo Elena, Ferrarese Roberto, Diotti Roberta A, Sampaolo Michela, Novazzi Federica, Dalla Gasperina Daniela, Focosi Daniele, Ferrari Davide, Locatelli Massimo, Clementi Massimo, Clementi Nicola, Maggi Fabrizio, Mancini Nicasio
Abstract excerpt
SARS-CoV-2 spike is evolving to maximize transmissibility and evade the humoral response. The massive genomic sequencing of SARS-CoV-2 isolates has led to the identification of single-point mutations and deletions, often having the recurrence of hotspots, associated with advantageous phenotypes. We report the isolation and molecular characterization of a SARS-CoV-2 strain, belonging to a lineage (C.36) not...
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