Article
Clock proteins and training modify exercise capacity in a daytime-dependent manner.
Proceedings of the National Academy of Sciences of the United States of America - 31 Aug 2021
Adamovich Yaarit, Dandavate Vaishnavi, Ezagouri Saar, Manella Gal, Zwighaft Ziv, Sobel Jonathan, Kuperman Yael, Golik Marina, Auerbach Asher, Itkin Maxim, Malitsky Sergey, Asher Gad
Abstract excerpt
Exercise and circadian biology are closely intertwined with physiology and metabolism, yet the functional interaction between circadian clocks and exercise capacity is only partially characterized. Here, we tested different clock mutant mouse models to examine the effect of the circadian clock and clock proteins, namely PERIODs and BMAL1, on exercise capacity. We found that daytime variance in endurance exercise...
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