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Diagnosis of Osteoarticular Tuberculosis: Multi-Targeted Loop-Mediated Isothermal Amplification Assay Versus Multiplex PCR

20 Aug 2021

Abstract excerpt

Aim: Diagnosis of osteoarticular tuberculosis (OATB) is quite challenging and there is an urgent need to design a prompt and precise diagnostic test. Methods: We developed a multi-targeted loop-mediated isothermal amplification (LAMP) assay using mpt64 (Rv1980c) and pstS1 (Rv0934) targets for the detection of Mycobacterium tuberculosis in OATB patients. Results: The sensitivities of 100 and 82.4% were obtained in...

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PMID: 34414775
DOI: 10.2217/fmb-2021-0030

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