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Investigation of Potential Molecular Biomarkers for Diagnosis and Prognosis of AFP-Negative HCC

1 Aug 2021

Abstract excerpt

BACKGROUND: Alpha-fetoprotein (AFP) is the most important diagnostic and prognostic index of hepatocellular carcinoma (HCC). AFP-positive HCC can be easily diagnosed based on the serum AFP level and typical imaging features, but a number of HCC patients are negative (AFP < 20 ng/mL) for AFP. Therefore, it is necessary to develop novel diagnostic and prognostic biomarkers for AFP-negative HCC. METHODS: RNA data...

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PMID: 34408477
DOI: 10.2147/ijgm.s323868

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