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Application of CRISPR-Cas9 Editing for Virus Engineering and the Development of Recombinant Viral Vaccines

1 Aug 2021

Abstract excerpt

CRISPR-Cas technology, discovered originally as a bacterial defense system, has been extensively repurposed as a powerful tool for genome editing for multiple applications in biology. In the field of virology, CRISPR-Cas9 technology has been widely applied on genetic recombination and engineering of genomes of various viruses to ask some fundamental questions about virus-host interactions. Its high efficiency,...

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PMID: 34406035
DOI: 10.1089/crispr.2021.0017

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