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Article

The clinical utility of exome and genome sequencing across clinical indications: a systematic review.

Human genetics - 1 Oct 2021

Shickh Salma, Mighton Chloe, Uleryk Elizabeth, Pechlivanoglou Petros, Bombard Yvonne

Abstract excerpt

Exome sequencing and genome sequencing have the potential to improve clinical utility for patients undergoing genetic investigations. However, evidence of clinical utility is limited to pediatric populations; we aimed to fill this gap by conducting a systematic review of the literature on the clinical utility of exome/genome sequencing across disease indications in pediatric and adult populations. MEDLINE, EMBASE...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 34368901
DOI: 10.1007/s00439-021-02331-x

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