Influences of the polymorphisms of the Sod2 gene (rs4880) on the motility and vigor of X- and Y-bearing sperm at different pH values.

doi:10.1016/j.biopha.2021.111993

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Influences of the polymorphisms of the Sod2 gene (rs4880) on the motility and vigor of X- and Y-bearing sperm at different pH values.

Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie - 1 Oct 2021

de Oliveira Paludo Francis Jackson, de Bittencourt Pasquali Matheus Augusto, de Vargas Amanda Rodrigues, de Oliveira Iara Bezerra, Gonçalves Luzia Valberligia Batista, Gelain Daniel Pens, Moreira José Cláudio Fonseca

Abstract excerpt

Superoxide dismutase 2 (SOD2) is an antioxidant enzyme that appears phylogenetically conserved. However, functional Sod2 polymorphisms have been studied, and the specific polymorphisms are related to activity alterations of the SOD2 enzyme. An example of a polymorphism of SOD2 is Val16Ala (rs4880), which has been identified in exon 2 of the human Sod2 gene. This polymorphism is recognized as a single nucleotide...

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Influences of the polymorphisms of the Sod2 gene (rs4880) on the motility and vigor of X- and Y-bearing sperm at different pH values.

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