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Article

Circulating trophoblast cell clusters for early detection of placenta accreta spectrum disorders

3 Aug 2021

Abstract excerpt

Placenta accreta spectrum (PAS) is a high-risk obstetrical condition associated with significant morbidity and mortality. Current clinical screening modalities for PAS are not always conclusive. Here, we report a nanostructure-embedded microchip that efficiently enriches both single and clustered circulating trophoblasts (cTBs) from maternal blood for detecting PAS. We discover a uniquely high prevalence of...

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PMID: 34344888
DOI: 10.1038/s41467-021-24627-2

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