[Heart muscle proteins of an inbred mouse strain carrying the autosomal-recessive form of generalized myodystrophy].

Abstract excerpt

The study of the polypeptide structure of cardiac muscle proteins of the inbred mice 129 Re + dy/dy by two-dimensional electrophoresis has revealed quantitative and qualitative variations in four polypeptides out of 161 analyzed ones. It is supposed that the protein fractions N 14 and O 13 may contribute to the development of cardiac pathology. Gene-dosage dependence is identified for the fraction O 13.

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