Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Cats - telomere to telomere and nose to tail.

Trends in genetics : TIG - 1 Oct 2021

Lyons Leslie A

Abstract excerpt

Feline genomic medicine can decode human variants of uncertain significance (VUSs). Telomere-to-telomere genome assemblies are feasible for all felid species, supporting genetic evolution and speciation studies. Their highly conserved genomic organization compared to humans suggests cats may also decipher the intergenic variation affecting the 3D chromosome structures influencing gene regulation.

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Telomere
Share to Pets
Share to Cat Diseases

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Chromosomes, Mammalian

Share to Genetic Speciation

Share to Genome

Share to Genomics

Source

Identifiers

PMID: 34332790
DOI: 10.1016/j.tig.2021.06.001

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Cats - telomere to telomere and nose to tail.PMID 34332790Read ↗

Toward telomere-to-telomere cat genomes for precision medicine and conservation biology.Semantic proximity Read ↗

The feline genome.Semantic proximity Read ↗

The tiger genome and comparative analysis with lion and snow leopard genomes.Semantic proximity Read ↗

Phylogenomic evidence for ancient hybridization in the genomes of living cats (Felidae).Semantic proximity Read ↗

Initial sequence and comparative analysis of the cat genome.Semantic proximity Read ↗

A new domestic cat genome assembly based on long sequence reads empowers feline genomic medicine and identifies a novel gene for dwarfismSemantic proximity Read ↗

Exploiting genomic synteny in Felidae: cross-species genome alignments and SNV discovery can aid conservation management.Semantic proximity Read ↗

A high-resolution cat radiation hybrid and integrated FISH mapping resource for phylogenomic studies across Felidae.Semantic proximity Read ↗

Tracking footprints of artificial and natural selection signatures in breeding and non-breeding cats.Semantic proximity Read ↗

Comparative genomics of macaques and integrated insights into genetic variation and population historySemantic proximity Read ↗

A novel fishing cat reference genome for the evaluation of potential germline risk variantsSemantic proximity Read ↗

Structural variation in humans and our primate kin in the era of telomere-to-telomere genomes and pangenomicsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.