Research Note: Rous sarcoma growth differs among congenic lines containing major histocompatibility (B) complex recombinants.

doi:10.1016/j.psj.2021.101335

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Article

Research Note: Rous sarcoma growth differs among congenic lines containing major histocompatibility (B) complex recombinants.

Poultry science - 1 Sept 2021

Wilkinson N G, Kopulos R T, Yates L M, Briles W E, Taylor R L

Abstract excerpt

New arrangements of chicken major histocompatibility complex (MHC) class I BF and class IV BG genes are created through recombination. Characterizing the immune responses of such recombinants reveals genes or gene regions that contribute to immunity. Inbred Line UCD 003 (B17B17) served as the genetic background for congenic lines, each containing a unique MHC recombinant. After an initial cross to introduce a...

Topics

Animals
Chickens
Genotype
Histocompatibility
Major Histocompatibility Complex
Sarcoma, Avian

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Identifiers

PMID: 34329985
DOI: 10.1016/j.psj.2021.101335
PMCID: PMC8335648

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