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Article

MicroRNAs targeting VEGF are related to vascular dysfunction in preeclampsia

28 Jul 2021

Abstract excerpt

In preeclampsia (PE), pre-existent maternal endothelial dysfunction leads to impaired placentation and vascular maladaptation. The vascular endothelial growth factor (VEGF) pathway is essential in the placentation process and VEGF expression is regulated through post-transcriptional modification by microRNAs (miRNAs). We investigated the expression of VEGF-related circulating miR-16, miR-29b, miR-126, miR-155 and...

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PMID: 34318873
DOI: 10.1042/bsr20210874

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