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Determination of genetic effects and functional SNPs of bovine HTR1B gene on milk fatty acid traits.

BMC genomics - 27 Jul 2021

Cao Mingyue, Shi Lijun, Peng Peng, Han Bo, Liu Lin, Lv Xiaoqing, Ma Zhu, Zhang Shengli, Sun Dongxiao

Abstract excerpt

BACKGROUND: Our previous genome-wide association study (GWAS) on milk fatty acid traits in Chinese Holstein cows revealed, the SNP, BTB-01556197, was significantly associated with C10:0 at genome-wide level (P = 0.0239). It was located in the down-stream of 5-hydroxytryptamine receptor 1B (HTR1B) gene that has been shown to play an important role in the regulation of fatty acid oxidation. Hence, we considered it...

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Cattle
Fatty Acids
Genome-Wide Association Study
Milk
Polymorphism, Single Nucleotide

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 34315401
DOI: 10.1186/s12864-021-07893-8
PMCID: PMC8314477

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