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Article

Major histocompatibility complex class II genetic diversity and the genetic influence on gut microbiota in Guizhou minipigs.

Folia microbiologica - 1 Dec 2021

Yao Gang, Fan Min, Zhang Jian, Wu Yanjun, Zhao Hai, Zhang Hui, Li Longfei, Wu Shuguang

Abstract excerpt

Major histocompatibility complex (MHC) is an important complex that presents antigen to T cells. The second exon of swine MHC (SLA) class II genes has antigen binding sites that bind with extracellular antigen. Populations with high MHC gene diversity result in low gut microbiota, and individuals with MHC gene heterozygote have lower gut microbiota diversity than that of homozygote. The pig is an animal with...

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PMID: 34309822
DOI: 10.1007/s12223-021-00903-y

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