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Article

Loss of function of a DMR6 ortholog in tomato confers broad-spectrum disease resistance.

Proceedings of the National Academy of Sciences of the United States of America - 6 Jul 2021

Thomazella Daniela Paula de Toledo, Seong Kyungyong, Mackelprang Rebecca, Dahlbeck Douglas, Geng Yu, Gill Upinder S, Qi Tiancong, Pham Julie, Giuseppe Priscila, Lee Clara Youngna, Ortega Arturo, Cho Myeong-Je, Hutton Samuel F, Staskawicz Brian

Abstract excerpt

Plant diseases are among the major causes of crop yield losses around the world. To confer disease resistance, conventional breeding relies on the deployment of single resistance (R) genes. However, this strategy has been easily overcome by constantly evolving pathogens. Disabling susceptibility (S) genes is a promising alternative to R genes in breeding programs, as it usually offers durable and broad-spectrum...

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Identifiers

PMID: 34215692
DOI: 10.1073/pnas.2026152118
PMCID: PMC8271637

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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