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Evolution, heterogeneity and global dispersal of cosmopolitan genotype of Dengue virus type 2.

Scientific reports - 29 Jun 2021

Yenamandra Surya Pavan, Koo Carmen, Chiang Suzanna, Lim Han Shi Jeri, Yeo Zhen Yuan, Ng Lee Ching, Hapuarachchi Hapuarachchige Chanditha

Abstract excerpt

Dengue virus type 2 (DENV-2) contributes substantially to the dengue burden and dengue-related mortality in the tropics and sub-tropics. DENV-2 includes six genotypes, among which cosmopolitan genotype is the most widespread. The present study investigated the evolution, intra-genotype heterogeneity and dispersal of cosmopolitan genotype to understand unique genetic characteristics that have shaped the molecular...

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Dengue
Dengue Virus
Evolution, Molecular
Genotype
Malaria Research and Control

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Mosquito-borne diseases and control

Viral Envelope Proteins

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PMID: 34188091
DOI: 10.1038/s41598-021-92783-y
PMCID: PMC8241877

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