Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Epithelial-to-mesenchymal transition contributes to the downregulation of progesterone receptor expression in endometriosis lesions

16 Jun 2021

Abstract excerpt

Endometriosis is a common, estrogen-dependent disease, in which endometrial tissue grows in the peritoneal cavity. These lesions often express low levels of progesterone receptors (PR), which potentially play an important role in the insufficient response to progestin treatment. Here, we uncover an interconnection between the downregulated PR expression and the epithelial-to-mesenchymal transition (EMT) in...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Endometrial and Cervical Cancer Treatments
Share to Endometriosis Research and Treatment
Share to Uterine Myomas and Treatments

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 34144151
DOI: 10.1016/j.jsbmb.2021.105943

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Epithelial-to-mesenchymal transition contributes to the downregulation of progesterone receptor expression in endometriosis lesionsPMID 34144151Read ↗

The influence of menstrual cycle and endometriosis on endometrial expression of epithelial-to-mesenchymal transition (EMT)-related genesSemantic proximity Read ↗

Endometriosis Malignant Transformation: Epigenetics as a Probable Mechanism in Ovarian TumorigenesisSemantic proximity Read ↗

Estrogen- and Progesterone (P4)-Mediated Epigenetic Modifications of Endometrial Stromal Cells (EnSCs) and/or Mesenchymal Stem/Stromal Cells (MSCs) in the Etiopathogenesis of EndometriosisSemantic proximity Read ↗

Steroid hormones regulate genome-wide epigenetic programming and gene transcription in human endometrial cells with marked aberrancies in endometriosisSemantic proximity Read ↗

Dysregulation of Plasma Membrane Transition (PMT) in Endometrial Epithelium: Implications for Infertility in EndometriosisSemantic proximity Read ↗

Overview of crosstalk between stromal and epithelial cells in the pathogenesis of adenomyosis and shared features with deep endometriotic nodulesSemantic proximity Read ↗

The epithelial-mesenchymal transition and the estrogen-signaling in ovarian cancer.Semantic proximity Read ↗

Upregulation of SPI1 in Ectopic Endometrium Contributes to an Invasive Phenotype.Semantic proximity Read ↗

Gene expression profiles separate endometriosis lesion subtypes and indicate a sensitivity of endometrioma to estrogen suppressive treatments through elevated ESR2 expressionSemantic proximity Read ↗

Molecular mechanisms underlying the inhibition of cell migration and invasion in endometriosis: Advances in pharmacological research (Review)Semantic proximity Read ↗

Changes in the Transcriptome of the Human Endometrial Ishikawa Cancer Cell Line Induced by Estrogen, Progesterone, Tamoxifen, and Mifepristone (RU486) as Detected by RNA-SequencingSemantic proximity Read ↗

Endometrial Gap Junction Expression - Early Indicators of Endometriosis and Integral to InvasivenessSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.