Plasma and stool metabolomics to identify microbiota derived-biomarkers of metabolic dysfunction-associated fatty liver disease: effect of PNPLA3 genotype.

doi:10.1007/s11306-021-01810-6

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Community

Back to search

Article

Plasma and stool metabolomics to identify microbiota derived-biomarkers of metabolic dysfunction-associated fatty liver disease: effect of PNPLA3 genotype.

Metabolomics : Official journal of the Metabolomic Society - 16 Jun 2021

Mazzini Flavia Noelia, Cook Frank, Gounarides John, Marciano Sebastián, Haddad Leila, Tamaroff Ana Jesica, Casciato Paola, Narvaez Adrián, Mascardi María Florencia, Anders Margarita, Orozco Federico, Quiróz Nicolás, Risk Marcelo, Gutt Susana, Gadano Adrián, Méndez García Celia, Marro Martin L, Penas-Steinhardt Alberto, Trinks Julieta

Abstract excerpt

INTRODUCTION: Non-invasive biomarkers are needed for metabolic dysfunction-associated fatty liver disease (MAFLD), especially for patients at risk of disease progression in high-prevalence areas. The microbiota and its metabolites represent a niche for MAFLD biomarker discovery. However, studies are not reproducible as the microbiota is variable. OBJECTIVES: We aimed to identify microbiota-derived metabolomic...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Biomarkers

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genotype

Share to Lipase

Share to Liver Disease Diagnosis and Treatment

Share to Membrane Proteins

Share to Metabolomics

Share to Microbiota

Share to Non-alcoholic Fatty Liver Disease

Source

Open in PubMed

Identifiers

PMID: 34137937
DOI: 10.1007/s11306-021-01810-6

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Plasma and stool metabolomics to identify microbiota derived-biomarkers of metabolic dysfunction-associated fatty liver disease: effect of PNPLA3 genotype.PMID 34137937Read ↗

Plasma and stool metabolomic biomarkers of non-alcoholic fatty liver disease in ArgentinaSemantic proximity Read ↗

Combined analysis of gut microbiota, diet and PNPLA3 polymorphism in biopsy-proven non-alcoholic fatty liver disease.Semantic proximity Read ↗

Multi-Omics Nutritional Approaches Targeting Metabolic-Associated Fatty Liver DiseaseSemantic proximity Read ↗

Epidemiological Study on the Interaction between the PNPLA3 (rs738409) and Gut Microbiota in Metabolic Dysfunction-Associated Steatotic Liver Disease.Semantic proximity Read ↗

Interaction Between the Gut Microbiome, Genetic and Clinical Risk Factors for Metabolic Dysfunction‐Associated Steatotic Liver Disease (MASLD) in Patients with Type 2 Diabetes Mellitus from Different Geographical Regions of ArgentinaSemantic proximity Read ↗

Integrative analysis of gut microbiota and fecal metabolites in metabolic associated fatty liver disease patientsSemantic proximity Read ↗

Links between gut microbiome composition and fatty liver disease in a large population sampleSemantic proximity Read ↗

Global epidemiology and implications of PNPLA3 I148M variant in MASLD: a systematic review and meta-analysisSemantic proximity Read ↗

Genetic Predictors of Comorbid Course of COVID-19 and MAFLD: A Comprehensive AnalysisSemantic proximity Read ↗

Microbial Dysbiosis Linked to Metabolic Dysfunction-Associated Fatty Liver Disease in Asians: Prevotella copri Promotes Lipopolysaccharide Biosynthesis and Network Instability in the Prevotella EnterotypeSemantic proximity Read ↗

Fecal Metagenomics and Metabolomics Identifying Microbial Signatures in Non-Alcoholic Fatty Liver DiseaseSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.