RT-qPCR Assays for Rapid Detection of the N501Y, 69-70del, K417N, and E484K SARS-CoV-2 Mutations: A Screening Strategy to Identify Variants With Clinical Impact.

doi:10.3389/fcimb.2021.672562

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RT-qPCR Assays for Rapid Detection of the N501Y, 69-70del, K417N, and E484K SARS-CoV-2 Mutations: A Screening Strategy to Identify Variants With Clinical Impact.

Frontiers in cellular and infection microbiology - 1 Jan 2021

Vega-Magaña Natali, Sánchez-Sánchez Rocío, Hernández-Bello Jorge, Venancio-Landeros Alberto Antony, Peña-Rodríguez Marcela, Vega-Zepeda Rosa Alejandra, Galindo-Ornelas Byron, Díaz-Sánchez Mauricio, García-Chagollán Mariel, Macedo-Ojeda Gabriela, García-González Octavio Patricio, Muñoz-Valle José Francisco

Abstract excerpt

Background: Several variants of the SARS-CoV-2 have been documented globally during the current COVID-19 pandemic. The N501Y, 69-70del, K417N, and E484K SARS-CoV-2 mutations have been documented among the most relevant due to their potential pathogenic biological effects. This study aimed to design, validate, and propose a fast real-time RT-qPCR assay to detect SARS-CoV-2 mutations with possible clinical and...

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PMID: 34123874
DOI: 10.3389/fcimb.2021.672562
PMCID: PMC8195289

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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