Article
SARS-CoV-2 mutations in Brazil: from genomics to putative clinical conditions.
Scientific reports - 7 Jun 2021
Timmers Luis Fernando Saraiva Macedo, Peixoto Julia Vasconcellos, Ducati Rodrigo Gay, Bachega José Fernando Ruggiero, de Mattos Pereira Leandro, Caceres Rafael Andrade, Majolo Fernanda, da Silva Guilherme Liberato, Anton Débora Bublitz, Dellagostin Odir Antônio, Henriques João Antônio Pegas, Xavier Léder Leal, Goettert Márcia Inês, Laufer Stefan
Abstract excerpt
Due to the high rate of transmissibility, Brazil became the new COVID-19 outbreak epicenter and, since then, is being monitored to understand how SARS-CoV-2 mutates and spreads. We combined genomic and structural analysis to evaluate genomes isolated from different regions of Brazil and show that the most prevalent mutations were located in the S, N, ORF3a and ORF6 genes, which are involved in different stages of...
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