Article
Development and evaluation of a loop-mediated isothermal amplification assay for clinical diagnosis of respiratory human adenoviruses emergent in China.
Diagnostic microbiology and infectious disease - 1 Sept 2021
Hong Lei, Li Jingyuan, Lv Junping, Chao Siqi, Xu Yaqing, Zou Dayang, Du Junjie, Lu Binan, Pang Zongran, Li Wenfeng, Liu Wei, Ke Yuehua, Hou Shuxun
Abstract excerpt
Three human adenovirus (HAdV) genotypes, HAdV-7, HAdV-14, and HAdV-55, emerged as the most prevalent variants in China over the past decade and caused both sporadic, fatal cases and frequent, large outbreaks. Early diagnosis is essential to control infections and endemics. Here, we established a loop-mediated isothermal amplification (LAMP) assay coupled with an instrument-free nucleic acid extraction device...
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