Article
Association of the CFTR gene with asthma and airway mucus hypersecretion.
PloS one - 1 Jan 2021
Crespo-Lessmann Astrid, Bernal Sara, Del Río Elisabeth, Rojas Ester, Martínez-Rivera Carlos, Marina Nuria, Pallarés-Sanmartín Abel, Pascual Silvia, García-Rivero Juan Luis, Padilla-Galo Alicia, Curto Elena, Cisneros Carolina, Serrano José, Baiget Montserrat, Plaza Vicente
Abstract excerpt
INTRODUCTION: Asthma with airway mucus hypersecretion is an inadequately characterized variant of asthma. While several studies have reported that hypersecreting patients may carry genetic variants in the cystic fibrosis transmembrane conductance regulator (CFTR) gene, many of those studies have been questioned for their numerous limitations and contradictory results. OBJECTIVES: (1) To determine the presence of...
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