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Small RNAs in Seminal Plasma as Novel Biomarkers for Germ Cell Tumors

13 May 2021

Abstract excerpt

Circulating miRNAs secreted by testicular germ cell tumors (TGCT) show great potential as novel non-invasive biomarkers for diagnosis of TGCT. Seminal plasma (SP) represents a biofluid closer to the primary site. Here, we investigate whether small RNAs in SP can be used to diagnose men with TGCTs or the precursor lesions, germ cell neoplasia in situ (GCNIS). Small RNAs isolated from SP from men with TGCTs (n =...

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PMID: 34067956
DOI: 10.3390/cancers13102346

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