Article
Vitamin D and COVID-19 susceptibility and severity in the COVID-19 Host Genetics Initiative: A Mendelian randomization study.
PLoS medicine - 1 Jun 2021
Butler-Laporte Guillaume, Nakanishi Tomoko, Mooser Vincent, Morrison David R, Abdullah Tala, Adeleye Olumide, Mamlouk Noor, Kimchi Nofar, Afrasiabi Zaman, Rezk Nardin, Giliberti Annarita, Renieri Alessandra, Chen Yiheng, Zhou Sirui, Forgetta Vincenzo, Richards J Brent
Abstract excerpt
BACKGROUND: Increased vitamin D levels, as reflected by 25-hydroxy vitamin D (25OHD) measurements, have been proposed to protect against COVID-19 based on in vitro, observational, and ecological studies. However, vitamin D levels are associated with many confounding variables, and thus associations described to date may not be causal. Vitamin D Mendelian randomization (MR) studies have provided results that are...
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