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Development of unenhanced CT-based imaging signature for BAP1 mutation status prediction in malignant pleural mesothelioma: Consideration of 2D and 3D segmentation.

Lung cancer (Amsterdam, Netherlands) - 1 Jul 2021

Xie Xiao-Jie, Liu Si-Yun, Chen Jian-You, Zhao Yi, Jiang Jie, Wu Li, Zhang Xing-Wen, Wu Yi, Duan Hui, He Bing, Luo Heng, Han Dan

Abstract excerpt

OBJECTIVES: We aimed to explore the feasibility of 2D and 3D radiomics signature based on the unenhanced computed tomography (CT) images to predict BRCA1-associated protein 1 (BAP1) gene mutation status for malignant pleural mesothelioma (MPM) patients. MATERIALS AND METHODS: 74 patients with MPM were retrospectively enrolled (22 mutant BAP1, 52 wild-type BAP1 demonstrated by Sanger sequencing). The radiomic...

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Identifiers

PMID: 34052706
DOI: 10.1016/j.lungcan.2021.04.023

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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