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Extracellular DNA of slow growers of mycobacteria and its contribution to biofilm formation and drug tolerance

26 May 2021

Abstract excerpt

DNA is basically an intracellular molecule that stores genetic information and carries instructions for growth and reproduction in all cellular organisms. However, in some bacteria, DNA has additional roles outside the cells as extracellular DNA (eDNA), which is an essential component of biofilm formation and hence antibiotic tolerance. Mycobacteria include life-threating human pathogens, most of which are slow...

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PMID: 34040029
DOI: 10.1038/s41598-021-90156-z

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