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Article

Host–pathogen immune feedbacks can explain widely divergent outcomes from similar infections

26 May 2021

Abstract excerpt

A long-standing question in infection biology is why two very similar individuals, with very similar pathogen exposures, may have very different outcomes. Recent experiments have found that even isogenic Drosophila melanogaster hosts, given identical inoculations of some bacterial pathogens at suitable doses, can experience very similar initial bacteria proliferation but then diverge to either a lethal infection...

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PMID: 34034518
DOI: 10.1098/rspb.2021.0786

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