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Strain engraftment competition and functional augmentation in a multi-donor fecal microbiota transplantation trial for obesity

13 May 2021

Abstract excerpt

BACKGROUND: Donor selection is an important factor influencing the engraftment and efficacy of fecal microbiota transplantation (FMT) for complex conditions associated with microbial dysbiosis. However, the degree, variation, and stability of strain engraftment have not yet been assessed in the context of multiple donors. METHODS: We conducted a double-blinded randomized control trial of FMT in 87 adolescents...

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PMID: 33985595
DOI: 10.1186/s40168-021-01060-7

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