Article
EARN: an ensemble machine learning algorithm to predict driver genes in metastatic breast cancer.
BMC medical genomics - 7 May 2021
Mirsadeghi Leila, Haji Hosseini Reza, Banaei-Moghaddam Ali Mohammad, Kavousi Kaveh
Abstract excerpt
BACKGROUND: Today, there are a lot of markers on the prognosis and diagnosis of complex diseases such as primary breast cancer. However, our understanding of the drivers that influence cancer aggression is limited. METHODS: In this work, we study somatic mutation data consists of 450 metastatic breast tumor samples from cBio Cancer Genomics Portal. We use four software tools to extract features from this data....
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