Article
Effects of advanced maternal age and acute prenatal alcohol exposure on mouse offspring growth and craniofacial phenotype.
Alcoholism, clinical and experimental research - 1 Jul 2021
Draghici Diana, Barr Kevin, Hardy Daniel B, Allman Brian L, Willmore Katherine E
Abstract excerpt
BACKGROUND: Prenatal alcohol exposure (PAE) can result in developmental defects that include growth restriction, craniofacial anomalies, and cognitive behavioral deficits, though the presence and severity of these adverse outcomes can vary dramatically among exposed individuals. Preclinical animal models have demonstrated that the dose and timing of PAE account for much, but not all, of this phenotypic variation,...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
