Reexamining the optimal nuchal translucency cutoff for diagnostic testing in the cell-free DNA and microarray era: results from the Victorian Perinatal Record Linkage study.

doi:10.1016/j.ajog.2021.03.050

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Article

Reexamining the optimal nuchal translucency cutoff for diagnostic testing in the cell-free DNA and microarray era: results from the Victorian Perinatal Record Linkage study.

American journal of obstetrics and gynecology - 1 Nov 2021

Hui Lisa, Pynaker Cecilia, Bonacquisto Leonard, Lindquist Anthea, Poulton Alice, Kluckow Eliza, Hutchinson Briohny, Norris Fiona, Pertile Mark D, Gugasyan Lucy, Kulkarni Abhijit, Harraway James, Howden Amanda, McCoy Richard, da Silva Costa Fabricio, Menezes Melody, Palma-Dias Ricardo, Nisbet Debbie, Martin Nicole, Bethune Michael, Poulakis Zeffie, Halliday Jane

Abstract excerpt

BACKGROUND: The American College of Obstetricians and Gynecologists and the Society for Maternal-Fetal Medicine recently recommended offering genetic counseling and diagnostic testing for enlarged nuchal translucency at ≥3.0 mm, regardless of previous negative screening with noninvasive prenatal testing. OBJECTIVE: This study aimed to perform a population-based, individual record linkage study to determine the...

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PMID: 33957116
DOI: 10.1016/j.ajog.2021.03.050

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

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