Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

DOCK8-related Immunodeficiency Syndrome (DIDS): Report of Novel Mutations in Iranian Patients.

Journal of molecular neuroscience : MN - 1 Dec 2021

Yousefnezhad Sahar, Gharesouran Jalal, Ghafouri-Fard Soudeh, Hosseinzadeh Hassan, Ahmadian-Heris Javad, Jafari-Rouhi Amir Hossein, Taheri Mohammad, Rezazadeh Maryam

Abstract excerpt

DOCK8 immunodeficiency syndrome (DIDS) is a rare autosomal recessive (AR) disorder characterized by elevated serum IgE levels, eosinophilia, recurrent cutaneous infections, severe eczema, and sinopulmonary and gastrointestinal infections. This syndrome is a multisystem disease that is associated with both immune deficiency and neurological complications. In this study, we describe the clinical characteristics of...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Child
Share to Guanine Nucleotide Exchange Factors

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Homozygote

Share to Mutation

Share to Phenotype

Share to Primary Immunodeficiency Diseases

Source

Identifiers

PMID: 33948880
DOI: 10.1007/s12031-021-01843-5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

DOCK8-related Immunodeficiency Syndrome (DIDS): Report of Novel Mutations in Iranian Patients.PMID 33948880Read ↗

Exome-first Approach Identified Novel Homozygous Dedicator of Cytokinesis 8 (DOCK8) Mutations in Three Unrelated Iranian Pedigrees Suspected with Hyper-IgE Syndrome.Semantic proximity Read ↗

Recent Advances in DOCK8 Immunodeficiency Syndrome.Semantic proximity Read ↗

Clinical, immunological, and genetic description of a Mexican cohort of patients with DOCK8 deficiency.Semantic proximity Read ↗

Novel Variants of DOCK8 Deficiency in a Case Series of Iranian Patients.Semantic proximity Read ↗

Genetic, clinical, and laboratory markers for DOCK8 immunodeficiency syndrome.Semantic proximity Read ↗

Clinical and molecular profile of 20 patients with DOCK8 deficiency-a single-center experience from Southern India.Semantic proximity Read ↗

CRISPR/Cas-Based Gene Editing Strategies for DOCK8 Immunodeficiency SyndromeSemantic proximity Read ↗

Autosomal recessive hyper-IgE syndrome caused by DOCK8 gene mutation with new clinical features: a case report.Semantic proximity Read ↗

The clinical and laboratory spectrum of dedicator of cytokinesis 8 immunodeficiency syndrome in patients with a unique mutation.Semantic proximity Read ↗

DOCK8 deficiency: clinical and immunological phenotype and treatment options - a review of 136 patients.Semantic proximity Read ↗

Confirmation of Hyperimmunoglobulin E Syndrome in Two Patients with an Ocular Problem: Detection of Two New DOCK8 Mutations.Semantic proximity Read ↗

Insights into immunity from clinical and basic science studies of DOCK 8 immunodeficiency syndromeSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.