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Prenatal antidepressant exposure and sex differences in neonatal corpus callosum microstructure

4 May 2021

Abstract excerpt

Prenatal exposure to selective serotonin reuptake inhibitor (SSRI) antidepressants may influence white matter (WM) development, as previous studies report widespread microstructural alterations and reduced interhemispheric connectivity in SSRI-exposed infants. In rodents, perinatal SSRIs had sex-specific disruptions in corpus callosum (CC) axon architecture and connectivity; yet it is unknown whether SSRI-related...

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PMID: 33942888
DOI: 10.1002/dev.22125

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