Article
Robust Prediction of Immune Checkpoint Inhibition Therapy for Non-Small Cell Lung Cancer.
Frontiers in immunology - 1 Jan 2021
Jiang Jiehan, Jin Zheng, Zhang Yiqun, Peng Ling, Zhang Yue, Zhu Zhiruo, Wang Yaohui, Tong De, Yang Yining, Wang Jianfei, Yang Yadong, Xiao Kui
Abstract excerpt
Background: The development of immune checkpoint inhibitors (ICIs) is a revolutionary milestone in the field of immune-oncology. However, the low response rate is the major problem of ICI treatment. The recent studies showed that response rate to single-agent programmed cell death protein 1 (PD-1)/programmed cell death-ligand 1 (PD-L1) inhibition in unselected non-small cell lung cancer (NSCLC) patients is 25% so...
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