Successful treatment by on-demand glecaprevir and pibrentasvir for hepatitis C flare during R-CHOP in patients with diffuse large B-cell lymphoma: a case report.

doi:10.1186/s12879-021-06091-x

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Article

Successful treatment by on-demand glecaprevir and pibrentasvir for hepatitis C flare during R-CHOP in patients with diffuse large B-cell lymphoma: a case report.

BMC infectious diseases - 27 Apr 2021

Umemura Machiko, Suda Goki, Tsukamoto Shihori, Ebata Ko, Takahash Shinjiro, Sasaki Takashi, Nakajima Sae, Hirata Koji, Ozasa Mariko, Takano Masatoshi, Katagiri Masaki, Sakamoto Naoya

Abstract excerpt

BACKGROUND: In patients with hepatitis C virus (HCV) and malignant lymphoma, hepatitis C flare during R-CHOP can result in discontinuation of treatment. However, appropriate therapeutic strategies for managing hepatitis C flare during R-CHOP have not been established, and this issue is complicated by conflicting results regarding the use of direct-acting antivirals in patients with uncontrolled malignancies. CASE...

Topics

Aminoisobutyric Acids
Antineoplastic Combined Chemotherapy Protocols
Antiviral Agents
Benzimidazoles
Cyclophosphamide
Cyclopropanes
Doxorubicin
Genotype
Hepacivirus

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Hepatitis C

Humans

Lactams, Macrocyclic

Leucine

Lymphoma, Large B-Cell, Diffuse

Male

Middle Aged

Prednisone

Proline

Source

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Identifiers

PMID: 33906643
DOI: 10.1186/s12879-021-06091-x
PMCID: PMC8077834

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