Effect of Active Cancer on the Cardiac Phenotype: A Cardiac Magnetic Resonance Imaging-Based Study of Myocardial Tissue Health and Deformation in Patients With Chemotherapy-Naïve Cancer.

doi:10.1161/JAHA.120.019811

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Article

Effect of Active Cancer on the Cardiac Phenotype: A Cardiac Magnetic Resonance Imaging-Based Study of Myocardial Tissue Health and Deformation in Patients With Chemotherapy-Naïve Cancer.

Journal of the American Heart Association - 4 May 2021

Labib Dina, Satriano Alessandro, Dykstra Steven, Hansen Reis, Mikami Yoko, Guzzardi David G, Slavikova Zdenka, Feuchter Patricia, Flewitt Jacqueline, Rivest Sandra, Sandonato Rosa, Lydell Carmen P, Howarth Andrew G, Kolman Louis, Clarke Brian, Paterson D Ian, Oudit Gavin Y, Pituskin Edith, Cheung Winson Y, Lee Joon, White James A

Abstract excerpt

Background The overlap between cancer and cardiovascular care continues to expand, with intersections emerging before, during, and following cancer therapies. To date, emphasis has been placed on how cancer therapeutics influence downstream cardiac health. However, whether active malignancy itself influences chamber volumes, function, or overall myocardial tissue health remains uncertain. We sought to perform a...

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Identifiers

PMID: 33878890
DOI: 10.1161/JAHA.120.019811
PMCID: PMC8200726

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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