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Genomic prediction of hybrid crops allows disentangling dominance and epistasis.

Genetics - 17 May 2021

González-Diéguez David, Legarra Andrés, Charcosset Alain, Moreau Laurence, Lehermeier Christina, Teyssèdre Simon, Vitezica Zulma G

Abstract excerpt

We revisited, in a genomic context, the theory of hybrid genetic evaluation models of hybrid crosses of pure lines, as the current practice is largely based on infinitesimal model assumptions. Expressions for covariances between hybrids due to additive substitution effects and dominance and epistatic deviations were analytically derived. Using dense markers in a GBLUP analysis, it is possible to split specific...

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Chimera
Crops, Agricultural
Epistasis, Genetic
Forecasting
Hybridization, Genetic

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PMID: 33864072
DOI: 10.1093/genetics/iyab026
PMCID: PMC8128411

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