Article
Association of Interleukin-1α Functional Polymorphism with Risk of Chronic Periodontitis in Han Chinese Population.
Genetics research - 1 Jan 2021
She Xiaowei, Xiao Hua, Lu Shuang, Guo Lijun
Abstract excerpt
Chronic periodontitis (CP) is a common inflammatory illness affecting a large proportion of humans. Genetic factors are thought to play important roles in its onset and development. A functional polymorphism (rs1800587) in the promoter of the interleukin-1α gene (-889 C/T) has been found to confer risk of CP primarily in Europeans, but the association between this variant and CP in the Chinese population remains...
Topics
- Case-Control Studies
- China
- Chronic Periodontitis
- Gene Frequency
- Genetic Predisposition to Disease
- Genotype
- Humans
- Interleukin-1alpha
- Polymorphism, Single Nucleotide
