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Article

Large-Scale Phenomic and Genomic Analysis of Brain Asymmetrical Skew.

Cerebral cortex (New York, N.Y. : 1991) - 29 Jul 2021

Kong Xiang-Zhen, Postema Merel, Schijven Dick, Castillo Amaia Carrión, Pepe Antonietta, Crivello Fabrice, Joliot Marc, Mazoyer Bernard, Fisher Simon E, Francks Clyde

Abstract excerpt

The human cerebral hemispheres show a left-right asymmetrical torque pattern, which has been claimed to be absent in chimpanzees. The functional significance and developmental mechanisms are unknown. Here, we carried out the largest-ever analysis of global brain shape asymmetry in magnetic resonance imaging data. Three population datasets were used, UK Biobank (N = 39 678), Human Connectome Project (N = 1113),...

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Identifiers

PMID: 33836062
DOI: 10.1093/cercor/bhab075
PMCID: PMC8328207

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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