Article
Seven Novel Genes Related to Cell Proliferation and Migration of VHL-Mutated Pheochromocytoma.
Frontiers in endocrinology - 1 Jan 2021
Gao Shuai, Liu Longfei, Li Zhuolin, Pang Yingxian, Shi Jiaqi, Zhu Feizhou
Abstract excerpt
Pheochromocytoma, as a neuroendocrine tumor with the highest genetic correlation in all types of tumors, has attracted extensive attention. Von Hipper Lindau (VHL) has the highest mutation frequency among the genes associated with pheochromocytoma. However, the effect of VHL on the proteome of pheochromocytoma remains to be explored. In this study, the VHL knockdown (VHL-KD) PC12 cell model was established by RNA...
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